Small Molecule Screen Reveals Regulation of Survival Motor Neuron Protein Abundance by Ras Proteins
نویسندگان
چکیده
منابع مشابه
Small molecule screen reveals regulation of survival motor neuron protein abundance by Ras proteins.
Small molecule modulators of protein activity have proven invaluable in the study of protein function and regulation. While inhibitors of protein activity are relatively common, small molecules that can increase protein abundance are rare. Small molecule protein upregulators with targeted activities would be of value in the study of the mechanisms underlying loss-of-function diseases. We develo...
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ژورنال
عنوان ژورنال: ACS Chemical Biology
سال: 2013
ISSN: 1554-8929,1554-8937
DOI: 10.1021/cb300374h